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Open Access Review

Human metapneumovirus infections on the ICU: a report of three cases

Lenneke E M Haas13*, Natasja X de Rijk1 and Steven F T Thijsen2

Author Affiliations

1 Department of Intensive Care Medicine, Diakonessenhuis, Utrecht, The Netherlands

2 Department of Microbiology, Diakonessenhuis, Utrecht, The Netherlands

3 Diakonessenhuis Utrecht, PO box 80250, 3508, TG, Utrecht, the Netherlands

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Annals of Intensive Care 2012, 2:30  doi:10.1186/2110-5820-2-30

Published: 19 July 2012

Abstract

Although human metapneumovirus (hMPV) is primarily known as a causative agent of respiratory tract infections in children, the virus also can cause respiratory infections in adults. hMPV infections tend to be mild and are self-limiting, but the infections can be severe in the elderly and immunocompromised patients. Because hMPV infection is quite common, it should be considered in every patient with respiratory failure in the intensive care unit (ICU). We describe three adult patients, including a young pregnant woman, with hMPV infection who required admission to our ICU. Two of them developed respiratory failure with indication for mechanical ventilation.

Keywords:
Human metapneumovirus; hMPV; Respiratory tract infections; Intensive care; Respiratory insufficiency